SPON1

Entrez Summary: N/A
UniProt Summary: Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Expression Distribution

LBD domain binding
negative regulation of amyloid-beta formation
negative regulation of amyloid precursor protein catabolic process
positive regulation of amyloid precursor protein catabolic process
positive regulation of protein processing
positive regulation of protein maturation
regulation of amyloid-beta formation
regulation of amyloid precursor protein catabolic process
regulation of protein processing
regulation of protein maturation
positive regulation of protein binding
extracellular matrix structural constituent
negative regulation of cellular amide metabolic process
positive regulation of binding
regulation of protein binding
extracellular matrix
endoplasmic reticulum lumen
positive regulation of proteolysis
collagen-containing extracellular matrix
regulation of binding
regulation of cellular amide metabolic process
regulation of proteolysis
cell adhesion
biological adhesion
negative regulation of protein metabolic process
extracellular space
positive regulation of cellular protein metabolic process
positive regulation of protein metabolic process
positive regulation of molecular function
positive regulation of gene expression