ST8SIA2

Entrez Summary: N/A
UniProt Summary: May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
ganglioside biosynthetic process
sialic acid binding
N-glycan processing
ganglioside metabolic process
sialylation
glycosphingolipid biosynthetic process
ceramide biosynthetic process
oligosaccharide metabolic process
glycolipid biosynthetic process
glycosphingolipid metabolic process
ceramide metabolic process
sphingolipid biosynthetic process
glycolipid metabolic process
liposaccharide metabolic process
recycling endosome
membrane lipid biosynthetic process
sphingolipid metabolic process
membrane lipid metabolic process
early endosome
protein glycosylation
macromolecule glycosylation
glycosylation
glycoprotein biosynthetic process
glycoprotein metabolic process
carbohydrate metabolic process
amide biosynthetic process
lipid biosynthetic process
carbohydrate derivative biosynthetic process
Golgi membrane
cellular amide metabolic process
cellular lipid metabolic process
carbohydrate derivative metabolic process
lipid metabolic process
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process