STBD1

Entrez Summary: N/A
UniProt Summary: Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosomes. {ECO:0000269|PubMed:20810658, ECO:0000269|PubMed:21893048, ECO:0000269|PubMed:24837458}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glycophagy
starch binding
glycogen binding
phagophore assembly site membrane
glycogen catabolic process
glucan catabolic process
polysaccharide binding
cellular polysaccharide catabolic process
polysaccharide catabolic process
selective autophagy
cellular carbohydrate catabolic process
T-tubule
glycogen metabolic process
cellular glucan metabolic process
glucan metabolic process
ficolin-1-rich granule membrane
energy reserve metabolic process
tertiary granule membrane
cellular polysaccharide metabolic process
polysaccharide metabolic process
carbohydrate catabolic process
macroautophagy
cellular carbohydrate metabolic process
energy derivation by oxidation of organic compounds
process utilizing autophagic mechanism
autophagy
enzyme binding
generation of precursor metabolites and energy
carbohydrate metabolic process
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
leukocyte activation involved in immune response
cell activation involved in immune response