STMN4

Entrez Summary: N/A
UniProt Summary: Exhibits microtubule-destabilizing activity. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

microtubule depolymerization
protein depolymerization
microtubule polymerization or depolymerization
tubulin binding
regulation of microtubule polymerization or depolymerization
growth cone
cellular protein complex disassembly
regulation of microtubule cytoskeleton organization
regulation of microtubule-based process
protein-containing complex disassembly
neuron projection
cellular component disassembly
supramolecular fiber organization
microtubule cytoskeleton organization
regulation of cytoskeleton organization
neuron projection development
microtubule-based process
neuron development
Golgi apparatus
neuron differentiation
cytoskeleton organization
plasma membrane bounded cell projection organization
cell projection organization
regulation of organelle organization
generation of neurons
neurogenesis
cell development
protein-containing complex subunit organization