SUMF1

Gene Information
  • Official Symbol: SUMF1
  • Official Name: sulfatase modifying factor 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 285362
  • UniProt: Q8NBK3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17362
  • Expression level (log2 read counts): 3.65

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1