SVIP
Gene Information
- Official Symbol: SVIP
- Official Name: small VCP interacting protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 258010
- UniProt: Q8NHG7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly |
| regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly |
| negative regulation of ER-associated ubiquitin-dependent protein catabolic process |
| positive regulation of protein lipidation |
| positive regulation of lipoprotein metabolic process |
| regulation of protein lipidation |
| smooth endoplasmic reticulum membrane |
| regulation of ER-associated ubiquitin-dependent protein catabolic process |
| negative regulation of retrograde protein transport, ER to cytosol |
| negative regulation of protein exit from endoplasmic reticulum |
| regulation of lipoprotein metabolic process |
| regulation of retrograde protein transport, ER to cytosol |
| negative regulation of ERAD pathway |
| regulation of protein exit from endoplasmic reticulum |
| regulation of ERAD pathway |
| negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
| negative regulation of intracellular protein transport |
| negative regulation of response to endoplasmic reticulum stress |
| negative regulation of ubiquitin-dependent protein catabolic process |
| protein self-association |
| negative regulation of proteasomal protein catabolic process |
| negative regulation of intracellular transport |
| negative regulation of proteolysis involved in cellular protein catabolic process |
| tertiary granule membrane |
| ATPase binding |
| regulation of response to endoplasmic reticulum stress |
| negative regulation of cellular protein catabolic process |
| secretory granule membrane |
| anchored component of membrane |
| negative regulation of cellular protein localization |
| positive regulation of autophagy |
| regulation of proteasomal ubiquitin-dependent protein catabolic process |
| negative regulation of protein complex assembly |
| negative regulation of protein catabolic process |
| regulation of ubiquitin-dependent protein catabolic process |
| negative regulation of protein transport |
| regulation of proteasomal protein catabolic process |
| negative regulation of establishment of protein localization |
| regulation of proteolysis involved in cellular protein catabolic process |
| regulation of intracellular protein transport |
| regulation of cellular protein catabolic process |
| negative regulation of cellular catabolic process |
| negative regulation of catabolic process |
| regulation of autophagy |
| regulation of intracellular transport |
| negative regulation of proteolysis |
| positive regulation of cellular catabolic process |
| regulation of protein catabolic process |
| positive regulation of catabolic process |
| regulation of protein complex assembly |
| negative regulation of transport |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| regulation of cellular protein localization |
| myeloid leukocyte activation |
| Golgi membrane |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| regulated exocytosis |
| negative regulation of cellular component organization |
| regulation of protein transport |
| regulation of proteolysis |
| regulation of cellular response to stress |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| leukocyte mediated immunity |
| exocytosis |
| regulation of cellular catabolic process |
| regulation of cellular localization |
| leukocyte activation |
| endoplasmic reticulum membrane |
| regulation of cellular component biogenesis |
| regulation of catabolic process |
| secretion by cell |
| regulation of protein localization |
| negative regulation of cellular protein metabolic process |
| export from cell |
| cell activation |
| immune effector process |
| negative regulation of protein metabolic process |
| secretion |
| positive regulation of protein modification process |
| regulation of response to stress |
| positive regulation of cellular protein metabolic process |
| negative regulation of response to stimulus |
| positive regulation of protein metabolic process |
| regulation of protein modification process |
| regulation of transport |
| immune response |
| positive regulation of macromolecule biosynthetic process |
| vesicle-mediated transport |
| positive regulation of cellular biosynthetic process |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 8717
- Expression level (log2 read counts): 5.46
Expression Distribution
SVIP Expression in NALM6 Cells: 5.46
