SYCE3

Gene Information
  • Official Symbol: SYCE3
  • Official Name: synaptonemal complex central element protein 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 644186
  • UniProt: A1L190
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility. {ECO:0000250|UniProtKB:B5KM66}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9271
  • Expression level (log2 read counts): -7.68

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1