SYNE1
Gene Information
- Official Symbol: SYNE1
- Official Name: spectrin repeat containing nuclear envelope protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 23345
- UniProt: Q8NF91
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6507
- Expression level (log2 read counts): 5.61
SYNE1 Expression in NALM6 Cells: 5.61
