TCF15

Entrez Summary: N/A
UniProt Summary: May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

respiratory system process
mesenchymal to epithelial transition
establishment of epithelial cell apical/basal polarity
neuromuscular process controlling posture
paraxial mesoderm development
polarized epithelial cell differentiation
post-anal tail morphogenesis
establishment of apical/basal cell polarity
establishment of monopolar cell polarity
establishment or maintenance of monopolar cell polarity
eating behavior
establishment of epithelial cell polarity
regulation of extracellular matrix organization
respiratory gaseous exchange by respiratory system
morphogenesis of a polarized epithelium
establishment or maintenance of epithelial cell apical/basal polarity
establishment or maintenance of apical/basal cell polarity
establishment or maintenance of bipolar cell polarity
somitogenesis
RNA polymerase II transcription factor complex
somite development
feeding behavior
muscle organ morphogenesis
segmentation
neuromuscular process
establishment of cell polarity
mesoderm development
protein dimerization activity
establishment or maintenance of cell polarity
anterior/posterior pattern specification
mesenchyme development
ear development
skeletal system morphogenesis
muscle organ development
regionalization
skin development
morphogenesis of an epithelium
pattern specification process
DNA-binding transcription activator activity, RNA polymerase II-specific
muscle structure development