TEKT1

Entrez Summary: N/A
UniProt Summary: Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
A-366 10μM R03 exp115	-1.75
BI-6727 0.04μM R03 exp98	1.7

cilium movement involved in cell motility
cilium movement
cilium-dependent cell motility
cilium or flagellum-dependent cell motility
motile cilium
microtubule cytoskeleton
microtubule-based movement
microtubule
cilium assembly
cilium organization
plasma membrane bounded cell projection assembly
cell projection assembly
microtubule-based process
organelle assembly
localization of cell
cell motility
plasma membrane bounded cell projection organization
cell projection organization
locomotion
movement of cell or subcellular component