TEX261

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
5-Fluorouracil 2μM R00 exp1	1.7
Rifampicin 1μM R00 exp31	1.94

COPII adaptor activity
COPII-coated ER to Golgi transport vesicle
integral component of Golgi membrane
integral component of endoplasmic reticulum membrane
endoplasmic reticulum to Golgi vesicle-mediated transport
Golgi vesicle transport
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
intracellular transport
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
establishment of localization in cell
vesicle-mediated transport