TLE2

Gene Information
  • Official Symbol: TLE2
  • Official Name: TLE family member 2, transcriptional corepressor
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 7089
  • UniProt: Q04725
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9261
  • Expression level (log2 read counts): 3.4

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1