TMEFF2

Official Symbol: TMEFF2
Official Name: transmembrane protein with EGF like and two follistatin like domains 2
Aliases and Previous Symbols: N/A
Entrez ID: 23671
UniProt: Q9UIK5
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Kazal 2
Kazal 1

negative regulation of integrin biosynthetic process
regulation of integrin biosynthetic process
regulation of plasma membrane organization
negative regulation of stress fiber assembly
negative regulation of actin filament bundle assembly
wound healing, spreading of cells
epiboly involved in wound healing
epiboly
morphogenesis of an epithelial sheet
regulation of stress fiber assembly
regulation of actomyosin structure organization
regulation of actin filament bundle assembly
negative regulation of supramolecular fiber organization
negative regulation of cytoskeleton organization
negative regulation of cell migration
regulation of actin filament organization
negative regulation of cell motility
negative regulation of cellular component movement
negative regulation of locomotion
regulation of actin cytoskeleton organization
regulation of supramolecular fiber organization
negative regulation of organelle organization
regulation of actin filament-based process
morphogenesis of an epithelium
wound healing
regulation of cytoskeleton organization
tissue morphogenesis
response to wounding
negative regulation of cellular component organization
molecular function
regulation of cell migration
regulation of cell motility
animal organ morphogenesis
regulation of cellular component biogenesis
cell migration
regulation of locomotion
regulation of cellular component movement
localization of cell
cell motility
epithelium development