TMEM102

Entrez Summary: N/A
UniProt Summary: Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway. {ECO:0000269|PubMed:17828305}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of T cell chemotaxis
regulation of T cell chemotaxis
positive regulation of lymphocyte chemotaxis
regulation of lymphocyte chemotaxis
positive regulation of T cell migration
positive regulation of lymphocyte migration
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of T cell migration
regulation of lymphocyte migration
regulation of mitochondrial membrane permeability
regulation of membrane permeability
positive regulation of leukocyte chemotaxis
regulation of leukocyte chemotaxis
mitochondrial membrane organization
positive regulation of leukocyte migration
positive regulation of chemotaxis
regulation of mitochondrion organization
regulation of leukocyte migration
regulation of chemotaxis
mitochondrial transport
regulation of peptidyl-tyrosine phosphorylation
regulation of apoptotic signaling pathway
positive regulation of cell adhesion
mitochondrion organization
positive regulation of cell migration
positive regulation of cell motility
positive regulation of cellular component movement
positive regulation of locomotion
protein-containing complex
positive regulation of response to external stimulus
cell surface
regulation of cell adhesion
regulation of cell migration
membrane organization
regulation of cell motility
apoptotic process
regulation of locomotion
regulation of cellular component movement
programmed cell death
cell death