TMEM115

Entrez Summary: N/A
UniProt Summary: May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi. {ECO:0000269|PubMed:24806965}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Golgi transport complex
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Golgi cisterna membrane
endoplasmic reticulum to Golgi vesicle-mediated transport
protein glycosylation
macromolecule glycosylation
glycosylation
glycoprotein biosynthetic process
Golgi vesicle transport
glycoprotein metabolic process
Golgi membrane
carbohydrate derivative biosynthetic process
negative regulation of cell population proliferation
molecular function
Golgi apparatus
carbohydrate derivative metabolic process
identical protein binding
organonitrogen compound biosynthetic process
protein transport
intracellular transport
peptide transport
amide transport
establishment of protein localization
regulation of cell population proliferation
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport