TNFAIP8L1

Entrez Summary: N/A
UniProt Summary: Acts as a negative regulator of mTOR activity. {ECO:0000250|UniProtKB:Q8K288}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of TOR signaling
regulation of TOR signaling
negative regulation of intracellular signal transduction
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
regulation of apoptotic process
regulation of programmed cell death
negative regulation of response to stimulus
regulation of cell death
regulation of intracellular signal transduction