TRAF3IP3
Gene Information
- Official Symbol: TRAF3IP3
- Official Name: TRAF3 interacting protein 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 80342
- UniProt: Q9Y228
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
- UniProt Summary: May function as an adapter molecule that regulates TRAF3-mediated JNK activation. {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 13803
- Expression level (log2 read counts): 2.67