TRIM14

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	0/29
uterus	0/5

Expression Distribution

SPRY
zf-B box

negative regulation of viral transcription
regulation of viral transcription
negative regulation of viral process
positive regulation of NF-kappaB transcription factor activity
mitochondrial outer membrane
regulation of viral process
negative regulation of multi-organism process
regulation of symbiosis, encompassing mutualism through parasitism
positive regulation of DNA-binding transcription factor activity
regulation of DNA-binding transcription factor activity
molecular function
innate immune response
regulation of multi-organism process
zinc ion binding
defense response to other organism
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
positive regulation of molecular function
immune response