TRIM15

Gene Information

Official Symbol: TRIM15
Official Name: tripartite motif containing 15
Aliases and Previous Symbols: N/A
Entrez ID: 89870
UniProt: Q9C019
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 4275
Expression level (log2 read counts): -2.84

Expression Distribution

SPRY
zf-C3HC4
zf-B box

negative regulation of intracellular transport of viral material
regulation of intracellular transport of viral material
mesodermal cell fate determination
positive regulation of RIG-I signaling pathway
mesodermal cell fate commitment
negative regulation of viral release from host cell
regulation of RIG-I signaling pathway
regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
mesodermal cell differentiation
cell fate commitment involved in formation of primary germ layer
regulation of viral release from host cell
cell fate determination
mesoderm formation
mesoderm morphogenesis
regulation of defense response to virus
positive regulation of type I interferon production
negative regulation of viral life cycle
negative regulation of viral process
formation of primary germ layer
mesoderm development
regulation of type I interferon production
regulation of viral life cycle
positive regulation of NF-kappaB transcription factor activity
gastrulation
regulation of viral process
negative regulation of multi-organism process
positive regulation of immune effector process
regulation of symbiosis, encompassing mutualism through parasitism
cell fate commitment
positive regulation of DNA-binding transcription factor activity
negative regulation of locomotion
positive regulation of innate immune response
positive regulation of response to biotic stimulus
regulation of DNA-binding transcription factor activity
positive regulation of cytokine production
regulation of innate immune response
regulation of immune effector process
positive regulation of defense response
negative regulation of transport
positive regulation of multi-organism process