TSKU

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
LY2090314 0.003μM R08 exp500 no dilution day6	-1.8
Bortezomib 0.05μM R00 exp7	1.73

ciliary body morphogenesis
anterior commissure morphogenesis
corpus callosum morphogenesis
lateral ventricle development
corpus callosum development
central nervous system projection neuron axonogenesis
ventricular system development
central nervous system neuron axonogenesis
central nervous system neuron development
camera-type eye morphogenesis
eye morphogenesis
central nervous system neuron differentiation
negative regulation of Wnt signaling pathway
sensory organ morphogenesis
telencephalon development
camera-type eye development
eye development
regulation of Wnt signaling pathway
visual system development
sensory system development
axonogenesis
forebrain development
axon development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
plasma membrane bounded cell projection morphogenesis
cell projection morphogenesis
cell part morphogenesis
sensory organ development
cell morphogenesis involved in differentiation
neuron projection development
cell morphogenesis
brain development
head development
neuron development
cellular component morphogenesis
animal organ morphogenesis
central nervous system development
neuron differentiation
plasma membrane bounded cell projection organization