TSPAN2

Entrez Summary: N/A
UniProt Summary: May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

microglia development
microglia differentiation
macrophage differentiation
myelin sheath
astrocyte development
astrocyte differentiation
myeloid cell development
oligodendrocyte differentiation
myelination
glial cell development
axon ensheathment
ensheathment of neurons
myeloid leukocyte differentiation
glial cell differentiation
gliogenesis
myeloid cell differentiation
leukocyte differentiation
axon development
inflammatory response
hemopoiesis
hematopoietic or lymphoid organ development
immune system development
neuron projection development
brain development
head development
neuron development
central nervous system development
neuron differentiation
plasma membrane bounded cell projection organization
cell projection organization
defense response
integral component of plasma membrane
generation of neurons
neurogenesis
cell development