TUBGCP5

Entrez Summary: N/A
UniProt Summary: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 482/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	10/28
blood	18/28
bone	21/26
breast	22/33
central nervous system	41/56
cervix	2/4
colorectal	11/17
esophagus	9/13
fibroblast	1/1
gastric	10/16
kidney	12/21
liver	16/20
lung	54/75
lymphocyte	13/16
ovary	17/26
pancreas	15/24
peripheral nervous system	14/16
plasma cell	11/15
prostate	1/1
skin	9/24
soft tissue	5/9
thyroid	1/2
upper aerodigestive	17/22
urinary tract	17/29
uterus	2/5

Expression Distribution

equatorial microtubule organizing center
microtubule nucleation by interphase microtubule organizing center
gamma-tubulin ring complex
microtubule nucleation by microtubule organizing center
microtubule minus-end binding
gamma-tubulin complex
microtubule nucleation
gamma-tubulin binding
microtubule polymerization
microtubule polymerization or depolymerization
cytoplasmic microtubule organization
protein polymerization
spindle assembly
spindle pole
spindle organization
meiotic cell cycle
microtubule binding
microtubule
supramolecular fiber organization
microtubule cytoskeleton organization
centrosome
microtubule-based process
mitotic cell cycle
organelle assembly
cellular protein-containing complex assembly
cell cycle process
cytoskeleton organization
cell cycle
reproductive process
reproduction
protein-containing complex assembly
protein-containing complex subunit organization