UCN2

Entrez Summary: N/A
UniProt Summary: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

corticotropin-releasing hormone receptor binding
corticotropin-releasing hormone receptor 2 binding
hormone binding
hormone activity
digestion
adenylate cyclase-activating G protein-coupled receptor signaling pathway
cAMP-mediated signaling
hormone-mediated signaling pathway
cyclic-nucleotide-mediated signaling
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
cellular response to nutrient levels
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
cellular response to extracellular stimulus
cellular response to external stimulus
second-messenger-mediated signaling
response to nutrient levels
response to extracellular stimulus
cellular response to hormone stimulus
response to hormone
cellular response to endogenous stimulus
G protein-coupled receptor signaling pathway
response to endogenous stimulus
extracellular space
intracellular signal transduction
extracellular region