UGT1A1
Gene Information
- Official Symbol: N/A
- Official Name: N/A
- Aliases and Previous Symbols: N/A
- Entrez ID: 54658
- UniProt: N/A
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Glyco tran 28 C |
| UDPGT |
GO Terms
| biphenyl catabolic process |
| bilirubin conjugation |
| cytochrome complex |
| biphenyl metabolic process |
| flavone metabolic process |
| heme catabolic process |
| porphyrin-containing compound catabolic process |
| pigment catabolic process |
| tetrapyrrole catabolic process |
| flavonoid glucuronidation |
| xenobiotic glucuronidation |
| endoplasmic reticulum chaperone complex |
| xenobiotic catabolic process |
| cellular response to ethanol |
| flavonoid metabolic process |
| cellular glucuronidation |
| UDP-glycosyltransferase activity |
| uronic acid metabolic process |
| glucuronate metabolic process |
| negative regulation of steroid metabolic process |
| benzene-containing compound metabolic process |
| retinoic acid binding |
| glucuronosyltransferase activity |
| steroid binding |
| heme metabolic process |
| enzyme inhibitor activity |
| retinoic acid metabolic process |
| estrogen metabolic process |
| cellular response to estradiol stimulus |
| porphyrin-containing compound metabolic process |
| acute-phase response |
| antibiotic catabolic process |
| cellular response to glucocorticoid stimulus |
| cellular response to corticosteroid stimulus |
| tetrapyrrole metabolic process |
| cofactor catabolic process |
| pigment metabolic process |
| acute inflammatory response |
| animal organ regeneration |
| negative regulation of lipid metabolic process |
| cellular response to alcohol |
| antibiotic metabolic process |
| retinoid metabolic process |
| diterpenoid metabolic process |
| regulation of steroid metabolic process |
| cellular response to antibiotic |
| terpenoid metabolic process |
| cellular hormone metabolic process |
| liver development |
| response to ethanol |
| hepaticobiliary system development |
| xenobiotic metabolic process |
| response to estradiol |
| isoprenoid metabolic process |
| response to glucocorticoid |
| regeneration |
| response to corticosteroid |
| cellular response to xenobiotic stimulus |
| cellular response to steroid hormone stimulus |
| response to starvation |
| monosaccharide metabolic process |
| hormone metabolic process |
| cellular response to toxic substance |
| response to nutrient |
| response to alcohol |
| steroid metabolic process |
| response to xenobiotic stimulus |
| response to antibiotic |
| response to lipopolysaccharide |
| response to molecule of bacterial origin |
| response to steroid hormone |
| enzyme binding |
| regulation of lipid metabolic process |
| cellular response to drug |
| gland development |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| cofactor metabolic process |
| aromatic compound catabolic process |
| carbohydrate metabolic process |
| organic cyclic compound catabolic process |
| protein heterodimerization activity |
| inflammatory response |
| response to nutrient levels |
| drug metabolic process |
| response to toxic substance |
| cellular response to lipid |
| monocarboxylic acid metabolic process |
| response to extracellular stimulus |
| regulation of hormone levels |
| cellular response to organic cyclic compound |
| cellular response to hormone stimulus |
| intracellular membrane-bounded organelle |
| response to bacterium |
| negative regulation of catalytic activity |
| response to lipid |
| protein homodimerization activity |
| response to hormone |
| carboxylic acid metabolic process |
| response to organic cyclic compound |
| endoplasmic reticulum membrane |
| cellular lipid metabolic process |
| oxoacid metabolic process |
| endoplasmic reticulum |
| response to drug |
| organic acid metabolic process |
| cellular response to oxygen-containing compound |
| organonitrogen compound catabolic process |
| negative regulation of molecular function |
| lipid metabolic process |
| cellular response to endogenous stimulus |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| integral component of plasma membrane |
| response to endogenous stimulus |
| response to oxygen-containing compound |
| small molecule metabolic process |
| organic substance catabolic process |
| cellular catabolic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| UMK57 1μM R01 exp59 | -1.74 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: N/A
| Tissue | Fraction Of Cell Lines Where Essential |
|---|
Essentiality in NALM6
- Essentiality Rank: 9937
- Expression level (log2 read counts): 1.58
Expression Distribution
UGT1A1 Expression in NALM6 Cells: 1.58
