VASH2

Entrez Summary: N/A
UniProt Summary: Angiogenesis inhibitor. Inhibits network formation by endothelial cells. {ECO:0000269|PubMed:16528006}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

labyrinthine layer blood vessel development
metallocarboxypeptidase activity
placenta blood vessel development
syncytium formation by plasma membrane fusion
cell-cell fusion
syncytium formation
labyrinthine layer development
embryonic placenta development
positive regulation of endothelial cell proliferation
regulation of endothelial cell proliferation
placenta development
positive regulation of angiogenesis
positive regulation of vasculature development
positive regulation of epithelial cell proliferation
actin binding
regulation of angiogenesis
regulation of vasculature development
regulation of epithelial cell proliferation
in utero embryonic development
reproductive structure development
reproductive system development
embryonic organ development
blood vessel development
vasculature development
cardiovascular system development
chordate embryonic development
embryo development ending in birth or egg hatching
developmental process involved in reproduction
circulatory system development
anatomical structure formation involved in morphogenesis
positive regulation of cell population proliferation
embryo development
regulation of anatomical structure morphogenesis
proteolysis
positive regulation of developmental process
reproductive process
reproduction
regulation of cell population proliferation
positive regulation of multicellular organismal process
extracellular region