VSTM2A

Entrez Summary: N/A
UniProt Summary: Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway. {ECO:0000269|PubMed:28052263}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

I-set
V-set

positive regulation of white fat cell proliferation
regulation of white fat cell proliferation
positive regulation of fat cell proliferation
positive regulation of brown fat cell differentiation
regulation of fat cell proliferation
regulation of brown fat cell differentiation
positive regulation of lipid storage
regulation of lipid storage
positive regulation of fat cell differentiation
positive regulation of lipid localization
response to BMP
cellular response to BMP stimulus
regulation of fat cell differentiation
regulation of lipid localization
cellular response to growth factor stimulus
response to growth factor
positive regulation of cell population proliferation
positive regulation of cell differentiation
identical protein binding
cellular response to endogenous stimulus
positive regulation of developmental process
response to endogenous stimulus
regulation of cell population proliferation
regulation of cell differentiation
extracellular region
positive regulation of gene expression