WISP3

Entrez Summary: N/A
UniProt Summary: Appears to be required for normal postnatal skeletal growth and cartilage homeostasis.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
GSK343 3μM R03 exp124	-1.92
Sulforaphane 9μM R08 exp526 no dilution day6	-1.74
Golgicide-A 4μM R03 exp122	1.74
GSK2606414 1μM R05 exp236	1.85

insulin-like growth factor binding
regulation of mitochondrial membrane potential
regulation of reactive oxygen species biosynthetic process
integrin binding
growth factor activity
heparin binding
regulation of reactive oxygen species metabolic process
extracellular matrix
regulation of membrane potential
cell adhesion
biological adhesion
negative regulation of cell death
endoplasmic reticulum
cell-cell signaling
mitochondrion
extracellular space
regulation of cell death