ZMAT2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 735/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	28/28
bone	26/26
breast	32/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	21/22
urinary tract	29/29
uterus	5/5

Expression Distribution

Screen	Score
Golgicide-A 2μM R03 exp121	-1.95
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	-1.8
BI-D1870 3.15μM R02 exp66	-1.71
Myriocin 25μM R06 exp293	1.9

zf-met
zf-C2H2 jaz

U4/U6 x U5 tri-snRNP complex
U2-type precatalytic spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions
RNA splicing
mRNA processing
mRNA metabolic process
zinc ion binding
RNA processing
DNA binding
RNA metabolic process
gene expression