ZNF503

Entrez Summary: N/A
UniProt Summary: May function as a transcriptional repressor. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Ixabepilone 0.004 to 0.005μM on day4 R04 exp184	-1.75
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	1.72

G1 to G0 transition involved in cell differentiation
G1 to G0 transition
neural precursor cell proliferation
nucleic acid binding
cell population proliferation
negative regulation of cell population proliferation
cell cycle process
cell cycle
regulation of cell population proliferation
negative regulation of gene expression