ZPBP2

Entrez Summary: N/A
UniProt Summary: Is implicated in sperm-oocyte interaction during fertilization. {ECO:0000250|UniProtKB:Q6X786}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	1/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

zona pellucida receptor complex
acrosome assembly
secretory granule organization
binding of sperm to zona pellucida
sperm-egg recognition
cell-cell recognition
cell body
acrosomal vesicle
cellular component assembly involved in morphogenesis
single fertilization
spermatid development
spermatid differentiation
fertilization
cell recognition
germ cell development
vesicle organization
cellular process involved in reproduction in multicellular organism
endomembrane system organization
spermatogenesis
male gamete generation
developmental process involved in reproduction
gamete generation
organelle assembly
cellular component morphogenesis
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
anatomical structure formation involved in morphogenesis
multi-organism reproductive process
reproductive process
reproduction
cell development
extracellular region