ZSWIM5

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	1.77
PFI-2 4μM R05 exp239	2.07

Cul2-RING ubiquitin ligase complex
regulation of axon guidance
regulation of axonogenesis
regulation of chemotaxis
regulation of cell morphogenesis involved in differentiation
regulation of cell morphogenesis
regulation of neuron projection development
regulation of neuron differentiation
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of neurogenesis
zinc ion binding
regulation of nervous system development
regulation of cell development
regulation of locomotion
regulation of cellular component movement
regulation of anatomical structure morphogenesis
regulation of response to external stimulus
generation of neurons
extracellular space
neurogenesis
regulation of cell differentiation