ADAM2
Gene Information
- Official Symbol: ADAM2
- Official Name: ADAM metallopeptidase domain 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 2515
- UniProt: Q99965
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 18605
- Expression level (log2 read counts): -7.68
ADAM2 Expression in NALM6 Cells: -7.68
