ANAPC13
Gene Information
- Official Symbol: ANAPC13
- Official Name: anaphase promoting complex subunit 13
- Aliases and Previous Symbols: N/A
- Entrez ID: 25847
- UniProt: Q9BS18
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:15060174, ECO:0000269|PubMed:18485873}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5903
- Expression level (log2 read counts): 4.73
ANAPC13 Expression in NALM6 Cells: 4.73
