UniProt Summary: Could induce apoptosis in a BH3 domain-dependent manner. The direct interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity. {ECO:0000269|PubMed:23055042}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
mitochondrial outer membrane permeabilization
positive regulation of mitochondrial membrane permeability involved in apoptotic process
mitochondrial outer membrane permeabilization involved in programmed cell death
positive regulation of mitochondrial membrane permeability
positive regulation of membrane permeability
regulation of mitochondrial membrane permeability involved in apoptotic process
apoptotic mitochondrial changes
regulation of mitochondrial membrane potential
regulation of mitochondrial membrane permeability
regulation of membrane permeability
mitochondrial membrane organization
mitochondrial transport
apoptotic signaling pathway
regulation of membrane potential
mitochondrion organization
membrane organization
apoptotic process
programmed cell death
cell death
mitochondrion
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)