C6orf106
Gene Information
- Official Symbol: ILRUN
- Official Name: inflammation and lipid regulator with UBA-like and NBR1-like domains
- Aliases and Previous Symbols: N/A
- Entrez ID: 64771
- UniProt: Q9H6K1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| negative regulation of defense response to virus |
| phagophore assembly site |
| negative regulation of protein localization to nucleus |
| negative regulation of type I interferon production |
| negative regulation of DNA binding |
| negative regulation of tumor necrosis factor production |
| negative regulation of tumor necrosis factor superfamily cytokine production |
| autophagosome |
| regulation of defense response to virus |
| ubiquitin binding |
| negative regulation of response to biotic stimulus |
| negative regulation of cellular protein localization |
| regulation of protein localization to nucleus |
| negative regulation of immune effector process |
| regulation of DNA binding |
| regulation of type I interferon production |
| regulation of tumor necrosis factor production |
| regulation of tumor necrosis factor superfamily cytokine production |
| macroautophagy |
| negative regulation of binding |
| negative regulation of defense response |
| negative regulation of multi-organism process |
| autophagy |
| process utilizing autophagic mechanism |
| negative regulation of cytokine production |
| negative regulation of response to external stimulus |
| regulation of binding |
| negative regulation of immune system process |
| regulation of immune effector process |
| regulation of response to biotic stimulus |
| regulation of cellular protein localization |
| regulation of cytokine production |
| regulation of defense response |
| innate immune response |
| regulation of multi-organism process |
| regulation of cellular localization |
| defense response to other organism |
| regulation of protein localization |
| regulation of response to external stimulus |
| negative regulation of molecular function |
| negative regulation of multicellular organismal process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of response to stress |
| negative regulation of response to stimulus |
| regulation of immune system process |
| cellular catabolic process |
| immune response |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 1/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 16169
- Expression level (log2 read counts): 5.8
Expression Distribution
C6ORF106 Expression in NALM6 Cells: 5.8
