GPR87

Entrez Summary: N/A
UniProt Summary: Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. {ECO:0000269|PubMed:17905198, ECO:0000269|PubMed:19602589}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Dexamethasone 0.006μM R07 exp351	1.72
Resveratrol 16μM R03 exp147	1.75
BRD2 inhibitor II 20μM R07 exp341	1.81
MS023 7μM R03 exp135	1.88
Vinblastine 0.002μM R01 exp60	1.96
Dexamethasone 0.006 to 0.015μM on day4 R07 exp352	2.04
SB203580 25μM R03 exp149	2.18
Mubritinib 0.2μM R01 exp48	2.44

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution