HAUS3

Entrez Summary: N/A
UniProt Summary: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	-1.97
BAY-598 4μM R05 exp220	1.74
ABT-702 0.1μM R06 exp260	1.91
Mdivi-1 15μM R05 exp217	4.27

Gene	Correlation
NUP54	0.435

Global Fraction of Cell Lines Where Essential: 254/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	7/28
blood	7/28
bone	15/26
breast	15/33
central nervous system	26/56
cervix	3/4
colorectal	2/17
esophagus	3/13
fibroblast	0/1
gastric	7/16
kidney	7/21
liver	7/20
lung	16/75
lymphocyte	9/16
ovary	11/26
pancreas	8/24
peripheral nervous system	7/16
plasma cell	4/15
prostate	1/1
skin	14/24
soft tissue	5/9
thyroid	0/2
upper aerodigestive	6/22
urinary tract	12/29
uterus	2/5

Expression Distribution