IARS2
Gene Information
- Official Symbol: IARS2
- Official Name: isoleucyl-tRNA synthetase 2, mitochondrial
- Aliases and Previous Symbols: N/A
- Entrez ID: 55699
- UniProt: Q9NSE4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 678
- Expression level (log2 read counts): 7.77
IARS2 Expression in NALM6 Cells: 7.77
