Pfam Domains GO Terms
| IL10 |
| interleukin-20 receptor binding |
| interleukin-22 receptor binding |
| positive regulation of keratinocyte differentiation |
| positive regulation of epidermal cell differentiation |
| positive regulation of osteoclast differentiation |
| positive regulation of epidermis development |
| regulation of keratinocyte differentiation |
| positive regulation of myeloid leukocyte differentiation |
| positive regulation of epithelial cell differentiation |
| regulation of epidermal cell differentiation |
| regulation of osteoclast differentiation |
| positive regulation of tyrosine phosphorylation of STAT protein |
| regulation of tyrosine phosphorylation of STAT protein |
| positive regulation of receptor signaling pathway via JAK-STAT |
| regulation of epidermis development |
| positive regulation of receptor signaling pathway via STAT |
| positive regulation of myeloid cell differentiation |
| regulation of myeloid leukocyte differentiation |
| regulation of receptor signaling pathway via JAK-STAT |
| regulation of receptor signaling pathway via STAT |
| regulation of epithelial cell differentiation |
| positive regulation of leukocyte differentiation |
| cytokine activity |
| positive regulation of hemopoiesis |
| positive regulation of peptidyl-tyrosine phosphorylation |
| regulation of myeloid cell differentiation |
| regulation of peptidyl-tyrosine phosphorylation |
| regulation of leukocyte differentiation |
| regulation of inflammatory response |
| regulation of hemopoiesis |
| cytokine-mediated signaling pathway |
| regulation of defense response |
| positive regulation of cell differentiation |
| cellular response to cytokine stimulus |
| positive regulation of protein phosphorylation |
| positive regulation of phosphorylation |
| regulation of response to external stimulus |
| response to cytokine |
| positive regulation of phosphate metabolic process |
| positive regulation of phosphorus metabolic process |
| positive regulation of immune system process |
| positive regulation of protein modification process |
| positive regulation of developmental process |
| regulation of protein phosphorylation |
| regulation of response to stress |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| regulation of immune system process |
| positive regulation of signal transduction |
| positive regulation of protein metabolic process |
| positive regulation of multicellular organismal process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of cell differentiation |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of protein modification process |
| extracellular region |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Taxol 0.002μM R01 exp54 | -2.11 |
| Menadione 5μM R06 exp292 | -1.72 |
| HMS-I1 10μM R06 exp256 | -1.71 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution