KCNJ14
Gene Information
- Official Symbol: KCNJ14
- Official Name: potassium inwardly rectifying channel subfamily J member 14
- Aliases and Previous Symbols: N/A
- Entrez ID: 3770
- UniProt: Q9UNX9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6573
- Expression level (log2 read counts): 3.37
KCNJ14 Expression in NALM6 Cells: 3.37
