UniProt Summary: Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. {ECO:0000269|PubMed:22321063}.
Pfam DomainsGO Terms
Pfam Domains
LRR 4
GO Terms
mitochondrial nucleoid
nuclear envelope
cadherin binding
endoplasmic reticulum membrane
endoplasmic reticulum
RNA binding
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)