MGAT4C
Gene Information
- Official Symbol: MGAT4C
- Official Name: MGAT4 family member C
- Aliases and Previous Symbols: N/A
- Entrez ID: 25834
- UniProt: Q9UBM8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). {ECO:0000250, ECO:0000269|PubMed:10962001}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17489
- Expression level (log2 read counts): 3.43
MGAT4C Expression in NALM6 Cells: 3.43
