MKNK1
Gene Information
- Official Symbol: MKNK1
- Official Name: MAPK interacting serine/threonine kinase 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 8569
- UniProt: Q9BUB5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 12193
- Expression level (log2 read counts): 5.61
MKNK1 Expression in NALM6 Cells: 5.61
