MYH3
Gene Information
- Official Symbol: MYH3
- Official Name: myosin heavy chain 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 4621
- UniProt: P11055
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008].
- UniProt Summary: Muscle contraction.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7992
- Expression level (log2 read counts): 3.34
MYH3 Expression in NALM6 Cells: 3.34
