UniProt Summary: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000269|PubMed:10049942}.
Pfam DomainsGO Terms
Pfam Domains
V-set
GO Terms
cellular defense response
transmembrane signaling receptor activity
signaling receptor activity
regulation of innate immune response
regulation of response to biotic stimulus
cell surface
regulation of defense response
innate immune response
regulation of multi-organism process
defense response to other organism
regulation of response to external stimulus
regulation of immune response
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
integral component of plasma membrane
regulation of response to stress
regulation of immune system process
immune response
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)