NUBP2
Gene Information
- Official Symbol: NUBP2
- Official Name: nucleotide binding protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 10101
- UniProt: Q9Y5Y2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure. {ECO:0000250|UniProtKB:Q9R061, ECO:0000255|HAMAP-Rule:MF_03039}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 861
- Expression level (log2 read counts): 5.43
NUBP2 Expression in NALM6 Cells: 5.43
