UniProt Summary: Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
Rdx
GO Terms
response to selenium ion
antioxidant activity
cellular oxidant detoxification
cellular detoxification
detoxification
cellular response to toxic substance
response to toxic substance
response to inorganic substance
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)