ZMYM3
Gene Information
- Official Symbol: ZMYM3
- Official Name: zinc finger MYM-type containing 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 9203
- UniProt: Q14202
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010].
- UniProt Summary: Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:21834987}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15201
- Expression level (log2 read counts): 6.71
ZMYM3 Expression in NALM6 Cells: 6.71
