ACMSD
Gene Information
- Official Symbol: ACMSD
- Official Name: aminocarboxymuconate semialdehyde decarboxylase
- Aliases and Previous Symbols: N/A
- Entrez ID: 130013
- UniProt: Q8TDX5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Amidohydro 2 |
GO Terms
| regulation of quinolinate biosynthetic process |
| picolinic acid metabolic process |
| aminocarboxymuconate-semialdehyde decarboxylase activity |
| picolinic acid biosynthetic process |
| regulation of de novo NAD biosynthetic process from tryptophan |
| regulation of tryptophan metabolic process |
| negative regulation of quinolinate biosynthetic process |
| tryptophan catabolic process |
| indole-containing compound catabolic process |
| indolalkylamine catabolic process |
| regulation of coenzyme metabolic process |
| tryptophan metabolic process |
| indolalkylamine metabolic process |
| cellular biogenic amine catabolic process |
| amine catabolic process |
| indole-containing compound metabolic process |
| aromatic amino acid family catabolic process |
| regulation of cofactor metabolic process |
| pyridine-containing compound biosynthetic process |
| aromatic amino acid family metabolic process |
| regulation of nucleotide biosynthetic process |
| pyridine-containing compound metabolic process |
| secondary metabolic process |
| cellular biogenic amine metabolic process |
| cellular amine metabolic process |
| regulation of cellular amino acid metabolic process |
| amine metabolic process |
| hydrolase activity |
| regulation of cellular amine metabolic process |
| negative regulation of small molecule metabolic process |
| alpha-amino acid catabolic process |
| regulation of nucleotide metabolic process |
| cellular amino acid catabolic process |
| regulation of cellular ketone metabolic process |
| monocarboxylic acid biosynthetic process |
| alpha-amino acid metabolic process |
| carboxylic acid catabolic process |
| organic acid catabolic process |
| carboxylic acid biosynthetic process |
| organic acid biosynthetic process |
| cellular amino acid metabolic process |
| regulation of small molecule metabolic process |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| small molecule catabolic process |
| aromatic compound catabolic process |
| organic cyclic compound catabolic process |
| protein complex oligomerization |
| monocarboxylic acid metabolic process |
| small molecule biosynthetic process |
| zinc ion binding |
| carboxylic acid metabolic process |
| oxoacid metabolic process |
| organic acid metabolic process |
| organonitrogen compound catabolic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| organic cyclic compound biosynthetic process |
| organonitrogen compound biosynthetic process |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| protein-containing complex assembly |
| cellular nitrogen compound biosynthetic process |
| small molecule metabolic process |
| organic substance catabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| cellular catabolic process |
| protein-containing complex subunit organization |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 11406
- Expression level (log2 read counts): -0.25
Expression Distribution
ACMSD Expression in NALM6 Cells: -0.25
