BASP1
Gene Information
- Official Symbol: BASP1
- Official Name: brain abundant membrane attached signal protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 10409
- UniProt: P80723
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| BASP1 |
GO Terms
| regulation of metanephric ureteric bud development |
| positive regulation of metanephric ureteric bud development |
| thorax and anterior abdomen determination |
| zygotic determination of anterior/posterior axis, embryo |
| diaphragm development |
| positive regulation of metanephros development |
| metanephric mesenchyme development |
| mesenchymal to epithelial transition |
| tripartite regional subdivision |
| anterior/posterior axis specification, embryo |
| renal filtration cell differentiation |
| glomerular visceral epithelial cell differentiation |
| glomerular epithelial cell differentiation |
| kidney mesenchyme development |
| blastoderm segmentation |
| glomerular epithelium development |
| positive regulation of mesonephros development |
| regulation of metanephros development |
| regulation of mesonephros development |
| epithelial cell differentiation involved in kidney development |
| embryonic axis specification |
| COP9 signalosome |
| positive regulation of heart growth |
| positive regulation of kidney development |
| cell differentiation involved in kidney development |
| substantia nigra development |
| positive regulation of organ growth |
| anterior/posterior axis specification |
| glomerulus development |
| regulation of kidney development |
| embryonic pattern specification |
| neural nucleus development |
| regulation of heart growth |
| positive regulation of animal organ morphogenesis |
| metanephros development |
| midbrain development |
| axis specification |
| regulation of organ growth |
| segmentation |
| nephron epithelium development |
| nephron development |
| kidney epithelium development |
| growth cone |
| skeletal muscle organ development |
| vesicle |
| positive regulation of developmental growth |
| respiratory system development |
| gonad development |
| development of primary sexual characteristics |
| anterior/posterior pattern specification |
| transcription regulatory region DNA binding |
| mesenchyme development |
| transcription corepressor activity |
| protein domain specific binding |
| regulation of animal organ morphogenesis |
| positive regulation of growth |
| sex differentiation |
| kidney development |
| renal system development |
| muscle organ development |
| urogenital system development |
| regulation of developmental growth |
| regionalization |
| cytoskeleton |
| nuclear speck |
| reproductive structure development |
| reproductive system development |
| pattern specification process |
| muscle structure development |
| cell junction |
| developmental process involved in reproduction |
| regulation of growth |
| epithelial cell differentiation |
| brain development |
| head development |
| embryo development |
| central nervous system development |
| regulation of anatomical structure morphogenesis |
| epithelium development |
| negative regulation of transcription, DNA-templated |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| positive regulation of developmental process |
| negative regulation of cellular macromolecule biosynthetic process |
| reproductive process |
| reproduction |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| negative regulation of gene expression |
| positive regulation of multicellular organismal process |
| tissue development |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| UM0130462 0.025 to 0.035μM day4 R05 exp247 | -1.93 |
| MLN-4924 0.2μM R00 exp21 | -1.82 |
| Brefeldin A 0.02μM R00 exp8 | -1.78 |
| Doxycycline 10μM R00 exp18 | -1.77 |
| All-trans-Retinoic-Acid 40μM R07 exp334 | -1.74 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4193
- Expression level (log2 read counts): -0.35
Expression Distribution
BASP1 Expression in NALM6 Cells: -0.35
